Leaderboard

I've decided to allow commenting in thread. In the event that I need more space I'll request a mod split the topic for discussion and reference. However for now, I'm opening the thread for comment and critique. This is especially for the APTX analysis. Welcome one and all to Kyuu's Detective Conan Toxicology thread! I will be posting analysis of the drugs and toxins found in DC that have been used in conjunction with cases (Yes, that includes APTX). There are THREE CATEGORIES of drugs that I'll be doing: 1) Real (Drugs and Toxins that were 100% identified by the series.) 2) Theoretical (APTX basically) 3) Semi-theoretical (Drugs that are possible IRL, but are not identified by Gosho, and can be determined to some degree of accuracy using the information in manga canon) (unnamed poisons and Conan's tranquilizer mostly) Key Terms that you will need to know and understand before reading my analysis: LD50 - Dosage of a toxic agent that will cause death in 50% of treated animals LC50 - Concentration of a toxic agent that will cause death in 50% of the treated animals T1/2 - Biological half-life. How long it takes the concentration in the biological system to be halved. LOAEL - Lowest observable adverse effect level. The amount of a toxin that causes an observable negative effect (your basic symptoms of poisoning without dying, if you have ever seen a drug commercial, you should know most of them) Bioavailability - How much of a drug reaches circulation unchanged in a biological system. IV is always 100% bioavailability, as it is direct to circulatory system. ADME - Absorption, Distribution, Metabolism, Excretion Absorption - How a drug is/can be administered Distribution - how a drug is distributed throughout the body (and what barriers it needs to pass) Metabolism - how the drug is metabolized by the biological system Excretion - how the drug is expelled from the body Those are the main, if I come to a point where I need to explain the more complex terms, I shall append them. I will make every effort to make this easy to read and understand for all. Drugs will be completely analyzed most likely using Toxnet a lot. I'll be using some other resources as well as needed. Everything will be fully referenced. If you use this information for any reason, PLEASE do the same. The drugs currently in planned to be analyzed are: (links will be added as analysis are done) APTX Tetrodotoxin Potassium Cyanide Sea Snake Venom (erabutoxin) Curare (possibly from poison dart case) Batrachotoxin (possibly from the poison dart case) Chlorine Potassium Chloride Phosphoric Acid Carbon Monoxide Aconitine (by Kjeldahl) More may be added as I reread the chapters and watch the episodes that the ones omitted appeared in while I look everything up. If you want clarification please PM or leave comment on my profile. If you wish to critique feel free to do it in topic. Also, this is being done on my own time, so I'm not sure how many I can/will get done. The ones that I am sure of are the top 3, and Carbon Monoxide. Everything else depends on my time and schedule. That all said, I hope you all enjoy this new project of mine and find it illuminating.

Well this game is very easy... someone will be post a case and people will try to solve it. The max guesses are only 10 (all not each person) and the max time limit is a week per case. Once at least one of these things are reached or once the right answer was guessed, the answer will be revealed. The one with the right answer will be given a rep by the one who made the case. (It now depends on the one who made the case whether he/she wants to give one or not) I will start

I edited the first post and fit things to my opinion. I know so little people T-T Agree? Disagree? Kogoro-> Balthazar Ayumi-> Ayame-chan (A. Haibara) Mitsuhiko-> Kudo12XX Ai-> Raki Yusaku-> Maurice Eri-> Kenzi Sonoko-> Moonlit Flower Kazuha-> Shahooda Kobayashi-> knpce Takagi-> Meitantei Kiddo Chiba-> MeitanteiXX Akai-> Akazora Jodie-> Chekhov Gin- Mohorovicic Akako-> Akakata Criminal-> Assimofirst

Try another browser. Chrome or Mozilla, if you have it. Explorer doesn't work.

I beg to differ as most if not all anime have impressive animation in the first few episodes to nab the attention of potential viewers that tapers down the road. Once someone has already started watching a series, they might as well finish it, especially after having seen 7 episodes. Amping up the budget on the 8th episode, which only people who are practically guaranteed to finish the anime will see, won't exactly do much to boost viewership and ultimately sales. A-1 Pictures is currently working on SAO II, Shigatsu wa Kimi no Uso, and Nanatsu no Taizai, all of which are being given higher budgets than MK1412, so it's not like they have a lot of money to spare. Some anime save money to make top notch animation at climactic high points in the series, wether they be fight scenes or moments of tension and drama. But episode 8 wasn't anything that deserved more attention to detail than usual. The only thing I can fathom is that one of their key animators wasn't needed in one of the previous anime I listed for this past week and had time to work on MK1412, hence the slight but noticeable change in quality.