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File 946: Japanese Text Spoilers Text Spoiler translations by Spimer:

Did you read the flashback case about their first meeting? Because we know that they met in pre-school and not through their parents. They became friends when they were four years old, went to the same school and mostly the same class after that, grew up close to each other and became BFs. You never had a kid in your neighborhood that you kept being friends with for a long time or someone at school?

Thanks! So the implication is that, when her husband died (though Gosho's statement on said matter leaves that up in the air), Mary had both Masumi's and Shukichi's surnames changed, and, around the time that he graduated from high school, Mary (and Shuichi, as well, perhaps) decided that Shukichi needed a new surname, for his own safety, while Mary would take Masumi to America (though that was much later on), and either found a married couple with surname Haneda, or just had the names made up (perhaps James played a role in this, in either finding willing participants to this ruse, or even altering records) so it would appear that Shukichi was not related to Mary, Shuichi and Masumi. Though, if he's writing his real father's name down on a legal document that will be kept for records, then... Alternatively, Serinox suggested, on DCTP, that Shukichi's envelope doesn't really contain a marriage registration form, since it was Shiho/Ai who suggested that idea, in the first place, and even referred to the idea as "cliché." The manager, if he knew Shukichi well enough (or even less, since Yumi probably doesn't know that much, if anything about Shukichi's family and background) he could fake it. Instead, then, the old man may give us (and Shinichi/Conan) info about Shukichi's past by the end of the case—if this alternative theory is not so, and there really is a marriage registration form in Shukichi's envelope, then we may have Shinichi/Conan see the "Akai" part, without showing us that he saw that, and the last panel of the last page of File 947 will show us that, indeed, he saw that.

Don't worry—as I see it, you're doing pretty darn good!

Time to revive my favourite thread. I will be assisting Kyuu in the Tox project so you can also send me any of your queries if Kyuu is unavailable. ACONITINE Introduction: Aconitine is an Alkaloid present in the Aconitum species of Plants. Its roots are highly poisonous. Ironically, roots are often used in traditional Chinese medicine for treatment of Rheumatoid Arthritis. Structure : Chemical Formula: C34H47NO11 Appearance: Crystals LOAEL: 0.006 mg/kg LD50(GI [assumed]): 0.028 mg/kg LD50Perspective: 2-3 mg is lethal. LD50(IV mouse): 0.1 mg/kg LD50(IP mouse): 0.1 mg/kg LD50(SC mouse): 0.27 mg/kg LD50(Oral mouse): 0.1 mg/kg Perspective on LD50 of Aconite Toxicity: Aconitine is a fast acting toxin. Although it is seen that pure Aconitine crystals aren’t as toxic as raw aconite products. T1/2: 6-12 hours ADME Absorption: Gastrointestinal tract, Intravenous and Intramuscular. Distribution: Through the blood. Metabolism: Metabolised by CYP P450 enzyme in the Liver. Excretion: Urine. Mechanism of toxicity (aka: how it kills you): Information on the mechanism from Detective Conan is as follows : Aconitine is a paralytic nerve poison extracted from the leaves and roots of Aconitum species. Verdict: Correct. Technical explanation: The toxin acts on binds on voltage dependant Sodium channels present on the surface of Cardiac muscle, Skeletal Muscles and Neurons. They prolong the opening of Sodium channels, thus causing depolarisation phase to last longer causing an upstroke in the Action potential. As a result, the membrane cannot be repolarized. Translation for lay people: It allows Sodium ions to move inside the cell causing increased Sodium concentration leading to physical manifestations. Notes on accuracy in DC: Although it is true that Aconitine has neurotoxic properties, it only causes generalised muscular weakness. Its most adverse toxic effect is seen in the Heart. Death is often due to Ventricular Arrhythmia. Final note: I won’t be delving much into the treatment part but if by any 0.1% chance someone accidentally encounters such a situation, drinking strong coffee can actually hamper the progression of the poisoning. That DOES NOT mean you don’t need to go to a hospital. Something interesting: In numerous lab experiments, it has been observed that Tetrodotoxin is able to act as an antidote in Aconite poisoning since they both show mutual antagonistic effect towards each other. Of course, we don’t administer Tetrodotoxin as it is super lethal and there are way better drugs out there. But still, a poison used to kill another poison and acting like an antidote is pretty cool though :3

So I purchased all available volumes that were translated of the manga and am just about to run out of volumes as they only release one every few months. Initially I was a little annoyed with the name changes and the "Americanisation" of the manga but after a while it really grew on me. Firstly you have Aoyama Gosho's notes at the end of each chapter which is really a look back into the past... I just remember little things like him talking about his proud purchase of a Windows 95 pc rating it over a Mac , and his worries about the localisation of the anime when it was originally being released in English. They put in little clues, just specific words in bold that give you an idea as to how the case will unfold. You also just have way higher quality scans and consistency in translations... the earlier versions were pretty bad quality really. Yeah that's all, I'm not trying to demean the scanlation groups nor anyone that reads them, I just wanted to make people aware that the official translations have something to offer. I'm not saying not to read the scanlations, but if you have recently picked up the series and can't put up with the chopping visual and grammatical quality of the earlier chapters and have some money to spare I would recommend buying the volumes.