The case that Jinpei Matsuda stole the show in had such an antagonist, so, if he's going to play a role (well, as much as a dead person can play a role), then someone like the vengeful bomber who killed him will appear as well—Rei/Toru will take up the role Jinpei took, and this new bomber will take up the role of the old bomber.
We rarely—if ever—see any Tokyo MPD character who ranks above Superintendent, so I can't see Senior Superintendent Kiyonaga Matsumoto making an appearance, here.
Maybe in the manga case that will come out around the time Movie 22 does, we'll get something about Rei/Toru and Hyoue, and, in the movie, we'll get a hint towards that, with its own spin, perhaps even keyframed by Gosho.