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Here's a general guide. Movie 12, 13, 14, 15, and 16 all have an "OVA" labeled as "Magic Files" to go before or after each movie. After Magic File 6, Episode 694, 735, and 774 were aired as preludes to the movies that year. They aren't really overly connected, but usually just had a bit of dialogue for the movie at the end of each episode. If the pattern follows, we should see the episode for M20 on April 16th.You could watch almost all the movies regardless of where they "fit in", but if you wanted to watch the movies in relation to their air-dates... You could follow the list below. After Episode 54 - Movie 1 After Episode 97 - Movie 2 After Episode 140 - Movie 3 After Episode 186 - Movie 4 After Episode 231 - Movie 5 After Episode 275 - Movie 6 After Episode 315 - Movie 7 After Episode 356 - Movie 8 After Episode 393 - Movie 9 After Episode 434 - Movie 10 After Episode 470 - Movie 11 After Episode 504 - Movie 12 (Watch Magic File 2 before this movie) After Episode 535 - Movie 13 (Watch Magic File 3 before this movie) After Episode 570 - Movie 14 (Watch Magic File 4 after this movie) After Episode 613 - Movie 15 (Watch Magic File 5 after this movie) After Episode 655 - Movie 16 (Watch Magic File 6 before this movie) After Episode 694 - Movie 17 After Episode 735 - Movie 18 After Episode 774 - Movie 19

Time to revive my favourite thread. I will be assisting Kyuu in the Tox project so you can also send me any of your queries if Kyuu is unavailable. ACONITINE Introduction: Aconitine is an Alkaloid present in the Aconitum species of Plants. Its roots are highly poisonous. Ironically, roots are often used in traditional Chinese medicine for treatment of Rheumatoid Arthritis. Structure : Chemical Formula: C34H47NO11 Appearance: Crystals LOAEL: 0.006 mg/kg LD50(GI [assumed]): 0.028 mg/kg LD50Perspective: 2-3 mg is lethal. LD50(IV mouse): 0.1 mg/kg LD50(IP mouse): 0.1 mg/kg LD50(SC mouse): 0.27 mg/kg LD50(Oral mouse): 0.1 mg/kg Perspective on LD50 of Aconite Toxicity: Aconitine is a fast acting toxin. Although it is seen that pure Aconitine crystals aren’t as toxic as raw aconite products. T1/2: 6-12 hours ADME Absorption: Gastrointestinal tract, Intravenous and Intramuscular. Distribution: Through the blood. Metabolism: Metabolised by CYP P450 enzyme in the Liver. Excretion: Urine. Mechanism of toxicity (aka: how it kills you): Information on the mechanism from Detective Conan is as follows : Aconitine is a paralytic nerve poison extracted from the leaves and roots of Aconitum species. Verdict: Correct. Technical explanation: The toxin acts on binds on voltage dependant Sodium channels present on the surface of Cardiac muscle, Skeletal Muscles and Neurons. They prolong the opening of Sodium channels, thus causing depolarisation phase to last longer causing an upstroke in the Action potential. As a result, the membrane cannot be repolarized. Translation for lay people: It allows Sodium ions to move inside the cell causing increased Sodium concentration leading to physical manifestations. Notes on accuracy in DC: Although it is true that Aconitine has neurotoxic properties, it only causes generalised muscular weakness. Its most adverse toxic effect is seen in the Heart. Death is often due to Ventricular Arrhythmia. Final note: I won’t be delving much into the treatment part but if by any 0.1% chance someone accidentally encounters such a situation, drinking strong coffee can actually hamper the progression of the poisoning. That DOES NOT mean you don’t need to go to a hospital. Something interesting: In numerous lab experiments, it has been observed that Tetrodotoxin is able to act as an antidote in Aconite poisoning since they both show mutual antagonistic effect towards each other. Of course, we don’t administer Tetrodotoxin as it is super lethal and there are way better drugs out there. But still, a poison used to kill another poison and acting like an antidote is pretty cool though :3