The drug back then used to Kill Kouji would have been Silver Bullet wouldn't it? I'm not surprised its also killing people like APTX if Shiho used it the base for her research. (She heavily implied it was killing most of her test mice, and the Org was using it to kill people too.) I've speculated that the two projects are the same, just by different names, one in the hands of the Miyano parents, one in the hands of Shiho, and that seems to be confirmed now. I have made more than a few posts about it and it's on the wiki under the speculation section for Silver Bullet and APTX. Conan would have naturally been surprised that it was being used 17 years ago and asked Ai about it because he doesn't know of Silver Bullet. He didn't listen to Haibara's tapes all the way through. ( I recall there is a thread at DCTP which talks about what Conan knows and doesn't to help keep track of what has been only been revealed to the reader through private thoughts.) Also about the scissors and P T ON from PUT ON MASCARA it's extremely likely we are looking at a Japanese pun. Koji most likely didn't tightly grip the scissors for self defense but to make sure the mark of the scissors could not be removed from his body as it is part of the clue. By inserting a scissors related word, or something related to cut you can probably figure it out. The tap left on in the recent case is probably a cryptic pun clue in the same vein. My guess is that Koji was a witness to a key part of Amanda's assassination and was silenced. We might get a lead on a Black Organization member in the past because of this case, especially if we can figure out if they came back to tamper with the crime scene. ---- The Akai family timeline so far
Mr. Akai and Mrs. Sera are born and married. Mrs. Sera takes her husband's surname Akai.
?? years ago: Shuichi Akai is born.
28 years ago: Shukichi Akai is born.
17 years ago: Koji Haneda is killed with APTX 4869 (most likely the Miyano parents' version Silver Bullet). Shukichi is 11.
16-17 years ago: Masumi Akai is born in Japan. At this time, the middle brother is approximately 11-12 and in junior high.
Sometime after Masumi is conceived, her father dies. The time of the father's death is uncertain, but Masumi implies it affected the family names.
>14-15 years ago: Masumi and Shukichi start using the family name Sera instead of Akai.
14-15 years ago: Shukichi enters high school with the family name Sera. Shukichi is 13-14 and Masumi is ~2.
11-12 years ago: Shukichi graduates high school and changes his family name from Sera to Haneda. Shukichi is age 16-17 and Masumi is 4-5. (Masumi says all three siblings have different family names. Masumi has "Sera", Shuichi has "Akai", and Shukichi has "Haneda".)
5-10 years ago: Shuichi sends Masumi Jeet Kune Do videos. (Masumi is 6-11 and in elementary school)
5 years ago: Shuichi starts infiltrating the Black Organization and dating Akemi Miyano. Shukichi is 22-23 and Masumi is 11.
3 years ago: Mrs. Akai and Masumi move to America, Masumi goes to middle school in America.
2 years ago: Shuichi is uncovered as an FBI agent and is ejected from the Black Organization.
Current: Masumi comes back at the age of 16-17 to Japan. Shukichi has been living in Japan winning shogi awards.