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I've decided to allow commenting in thread. In the event that I need more space I'll request a mod split the topic for discussion and reference. However for now, I'm opening the thread for comment and critique. This is especially for the APTX analysis. Welcome one and all to Kyuu's Detective Conan Toxicology thread! I will be posting analysis of the drugs and toxins found in DC that have been used in conjunction with cases (Yes, that includes APTX). There are THREE CATEGORIES of drugs that I'll be doing: 1) Real (Drugs and Toxins that were 100% identified by the series.) 2) Theoretical (APTX basically) 3) Semi-theoretical (Drugs that are possible IRL, but are not identified by Gosho, and can be determined to some degree of accuracy using the information in manga canon) (unnamed poisons and Conan's tranquilizer mostly) Key Terms that you will need to know and understand before reading my analysis: LD50 - Dosage of a toxic agent that will cause death in 50% of treated animals LC50 - Concentration of a toxic agent that will cause death in 50% of the treated animals T1/2 - Biological half-life. How long it takes the concentration in the biological system to be halved. LOAEL - Lowest observable adverse effect level. The amount of a toxin that causes an observable negative effect (your basic symptoms of poisoning without dying, if you have ever seen a drug commercial, you should know most of them) Bioavailability - How much of a drug reaches circulation unchanged in a biological system. IV is always 100% bioavailability, as it is direct to circulatory system. ADME - Absorption, Distribution, Metabolism, Excretion Absorption - How a drug is/can be administered Distribution - how a drug is distributed throughout the body (and what barriers it needs to pass) Metabolism - how the drug is metabolized by the biological system Excretion - how the drug is expelled from the body Those are the main, if I come to a point where I need to explain the more complex terms, I shall append them. I will make every effort to make this easy to read and understand for all. Drugs will be completely analyzed most likely using Toxnet a lot. I'll be using some other resources as well as needed. Everything will be fully referenced. If you use this information for any reason, PLEASE do the same. The drugs currently in planned to be analyzed are: (links will be added as analysis are done) APTX Tetrodotoxin Potassium Cyanide Sea Snake Venom (erabutoxin) Curare (possibly from poison dart case) Batrachotoxin (possibly from the poison dart case) Chlorine Potassium Chloride Phosphoric Acid Carbon Monoxide Aconitine (by Kjeldahl) More may be added as I reread the chapters and watch the episodes that the ones omitted appeared in while I look everything up. If you want clarification please PM or leave comment on my profile. If you wish to critique feel free to do it in topic. Also, this is being done on my own time, so I'm not sure how many I can/will get done. The ones that I am sure of are the top 3, and Carbon Monoxide. Everything else depends on my time and schedule. That all said, I hope you all enjoy this new project of mine and find it illuminating.

(Ohh, first post! Alrighy then, here goes~ xP) ~~~~~~~~~~ Kai's eyes suddenly snapped open. She was lying on a cold hard bed, staring at a bland ceiling. 'What is this...?' She half muttered, half thought, frowning. She got up, and as she did so, felt like something was missing. She glanced down at her hand by instinct. 'Oh...' She realized. Her watch was gone. So were her wallet and her phone, as she felt her pockets. 'Huh...' Kai almost laughed. For some reason, she didn't really feel scared like she probably should've in this situation, but instead a sense of curiosity overwhelmed her. Where was she? What was she doing here? Who brought her here? And....for what? She glanced around the room, searching for hints that would lead her to answers. But the room was a disappointment. It was very simple, even a bit big for its decor consisting of only a bed and a table in the corner. Something that looked like a computer rested on the table, but it seemed too complicated for her to figure out. Kai wasn't as interested in the computer anyway. Instead, she cautiously walked towards the door. Or at least, what seemed like the door. It was a big rectangular panel, made of what seemed like metal. It had a few buttons on the side, and a fancy-looking frame around it. But what she noticed before all of that was that the door was glowing red. As she investigated her surroundings once more, she realized something: It was eerily quiet. There was no humming of furnaces or air conditioners, no drip-drop sounds of water, no murmurs through the walls. There was only silence. And even when she neared the door, when its light suddenly flashed and faded into a blue, it gracefully slid open as though it was waiting for her all along, still keeping the fragile silence. Kai raised her eyebrows. 'Here goes nothing...' She took a deep breath and stepped outside. ~~~~~ "AHHHHHHH!" Kai screamed for the first time in years. She turned around as fast as she could and ran like there was no tomorrow, so fast she almost tripped and fell. As she regained her balance, she glanced back every few seconds and saw that the robot-bunnies were gaining on her. "What....Is...This!?!?" Kai definitely had not been expecting this. Robot-bunnies? Who even came up with the idea anyway? She got to the end of the hallway and arrived at a fork. Frantically, she turned left, all the while keeping a close watch on the bunnies behind her. 'What do I do now?' She asked desperately to herself. 'Or rather, what can I do now!?" She kept running, but she knew she couldn't keep it up for long. There was nothing on her, and she didn't know a single thing about this place. The robot-bunnies would get here in a few seconds, even less, and if they caught her she was dead meat. Once again Kai glanced at the other doors along the hallway, ones exactly like the one she got out of. 'I really wonder if there are people there..' She tried to open one, but there being nothing on the outside - not even a handle or some buttons - she couldn't. The bunnies were a dozen meters away now. She couldn't run anymore, she was too tired and even if she tried, they would get her in a few seconds. The door was her only hope. 'Come on...!' She banged on the cold metal as hard as she could. Somebody..."Help!" She cried, still banging repeatedly on the door. "Is anyone there?? Help!!!" The bunnies were almost upon her now. I wonder how it feels to be killed by bunny rabbits...Kai thought as she shut her eyes tightly, fearing for the worst. ~~~~~~~~~ (C: Hope it was okay~)